CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 63 enrolled
Drug / intervention
Arabic, Gum +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03684993
NCT03684993Phase 3Completed

Effect of Gum Arabic (Acacia Gum) and Licorice (Glycyrrhiza Glabra) Mouthwashes Compared to Chlorhexidine Mouthwash on Caries Prevention and the Prevalence of Oral Side Effects in High Caries Risk Patients: A Randomized Controlled Clinical Trial

Cairo University·interventional·Posted Sep 26, 2018·Updated Feb 28, 2020

In Brief

A Phase 3 clinical trial evaluating Arabic, Gum, Licorice Root, and 1 other intervention for High Caries Risk Patients and 3 related conditions. Completed, enrolled 63 participants across 1 site.

Detailed Summary

This trial is to test the caries prevention effect of Arabic gum and Licorice root extracts compared to Chlorhexidine in high caries risk patients. The antimicrobial efficacy and oral side effects from using these mouthwashes will also be tested.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesEgypt
Collaborators--

Timeline

Phase 3CompletedFinished
20192020202120222023202420252026
First PostedSep 26, 2018
Enrollment StartDec 10, 2019
Primary CompletionJan 15, 2020
TodayJul 2, 2026
Enrollment to primary: 1 monthPosted 7.8 years ago

Interventions

Arabic, Gumdrug

natural gum of acacia tree: Antimicrobial, anti-inflammatory medicinal plant used as a traditional oral hygiene substance (anticariogenic). It is used in treating sore throats, colds, bronchitis, toothache, gingival bleeding and mouth ulcers.

Licorice Rootdrug

natural licorice, herbal plant to relieve coughs, sore throats, and gastric inflammation. flavouring and sweetening agent. it's anti-caries, soothing anti-inflammatory and anticancer properties benefit against oral diseases and dental caries

Chlorhexidinedrug

chemical agent used as a mouthwash against cariogenic bacteria. considered the gold standard