At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 18 enrolled
Drug / intervention
Sildenafil Citrate +1 moredrug
Likely dose
Sildenafil Citrate 50 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Sildenafil for Prevention of Swimming-Induced Pulmonary Edema (SIPE)
In Brief
A Phase 2 clinical trial evaluating Sildenafil Citrate and Placebo Oral Tablet for Edema, Pulmonary and 2 related conditions. Completed, enrolled 18 participants across 1 site.
Detailed Summary
This trial is testing the effectiveness of a single oral dose of sildenafil (50 mg) taken 1 hour before a provocative event on the subsequent development of swimming-induced pulmonary edema.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsEdema, Pulmonary, Immersion, Diving
CountriesUnited States
CollaboratorsUnited States Department of Defense
Timeline
Phase 2CompletedFinished
20192020202120222023202420252026
First PostedSep 2018
Enrollment StartJul 2019
Primary CompletionOct 2021
TodayJul 2026
First PostedSep 27, 2018
Enrollment StartJul 15, 2019
Primary CompletionOct 29, 2021
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 7.8 years ago
Interventions
Sildenafil Citratedrug
Oral sildenafil, 50 mg
Placebo Oral Tabletdrug
Placebo