CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 188 enrolled
Drug / intervention
Program A +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03687086
NCT03687086N/ACompleted

A Novel Mechanism for Helping Older Adults Discontinue Use of Sleeping Pills

University of California, Los Angeles·interventional·Posted Sep 27, 2018·Updated Apr 7, 2026

In Brief

A clinical study evaluating Program A and Program B for Sleep Initiation and Maintenance Disorders. Completed, enrolled 188 participants across 2 sites.

Detailed Summary

Sleeping medications, called hypnotics, are often prescribed for insomnia and are associated with adverse health outcomes in older adults. Response rates to hypnotic discontinuation programs are often inadequate, and many patients eventually resume use of hypnotics, suggesting that other mechanisms need to be targeted to achieve and sustain high rates of non-use. Current programs focus on the tapering of hypnotics and/or the treatment of insomnia symptoms. These programs employ strategies such as supervised gradual taper, cognitive behavioral therapy targeting hypnotic withdrawal, and/or cognitive behavioral therapy for insomnia. Evidence suggests that another mechanism involving "placebo" effects may be a viable target for achieving and sustaining higher discontinuation rates. Cognitive expectancies play a key role in producing placebo effects, which are characterized as real improvements in sleep arising from psychosocial aspects of treatment rather than drug effects alone. In this study, investigators are comparing two programs for discontinuing hypnotic medications-a program that addresses placebo effects associated with hypnotic use and a program that does not address these effects.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedSep 27, 2018
Enrollment StartDec 11, 2018
Primary CompletionNov 27, 2023
TodayJul 2, 2026
Enrollment to primary: 5.0 yearsPosted 7.8 years ago

Interventions

Program Aother

Cognitive behavioral therapy type A plus medications prepared in packaging type A.

Program Bother

Cognitive behavioral therapy type B plus medications in packaging type B.