At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Linear Energy Transfer (LET)-Optimized Intensity Modulated Proton Therapy (IMPT) as a Component of Definitive Chemoradiation for Newly Diagnosed Squamous Cell Carcinoma of the Anal Canal: a Feasibility Trial
In Brief
A Phase 2 clinical trial evaluating Cisplatin, Fluorouracil, and 3 other interventions for Anal Canal Squamous Cell Carcinoma and 8 related conditions. Completed, enrolled 8 participants across 1 site.
Detailed Summary
This phase II trial studies the side effects of LET-IMPT and standard chemotherapy, and how well they work in treating patients with newly diagnosed stage I-III anal canal squamous cell cancer. LET-IMPT is a type of radiation therapy that uses high energy proton "beamlets" to "paint" the radiation dose into the target and may help to kill tumor cells and shrink tumors. Giving LET-IMPT and standard chemotherapy may work better in treating patients with anal canal squamous cell cancer.
Study Details
Timeline
Interventions
Given IV
Given IV
Undergo LET-IMPT
Ancillary studies
Ancillary studies