CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 179 enrolled
Drug / intervention
EDP-938 Dose 1 +5 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03691623
NCT03691623Phase 2Completed

A Randomised, Phase 2a, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Pharmacokinetics and Antiviral Activity of Multiple Doses of Orally Administered EDP-938 Against Respiratory Syncytial Virus Infection in the Virus Challenge Model.

Enanta Pharmaceuticals, Inc·interventional·Posted Oct 2, 2018·Updated May 3, 2022

In Brief

A Phase 2 clinical trial evaluating EDP-938 Dose 1, EDP-938 Dose 2, and 3 other interventions for RSV Infection. Completed, enrolled 179 participants across 1 site.

Detailed Summary

A randomised, Phase 2a, double-blind, placebo-controlled study to evaluate the safety, pharmacokinetics and antiviral activity of multiple doses of orally administered EDP-938 in healthy subjects infected with RSV-A Memphis 37b. This study is designed to compare the antiviral effect of EDP-938 compared to a placebo control in the respiratory syncytial virus challenge model.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRSV Infection
CountriesUnited Kingdom

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedOct 2, 2018
Enrollment StartOct 15, 2018
Primary CompletionSep 30, 2019
Study CompletionOct 18, 2019
TodayJul 2, 2026
Enrollment to primary: 12 monthsPosted 7.8 years ago

Interventions

EDP-938 Dose 1drug

Oral suspension for 5 days

EDP-938 Dose 2drug

Oral suspension for 5 days

Placebodrug

Oral suspension for 5 days

EDP-938 Dose 3drug

Oral suspension for 5 days

EDP-938 Dose 4drug

Oral suspension for 5 days

Placebodrug

Oral suspension for 5 days