CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 35 enrolled
Drug / intervention
SAGE-217 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03692910
NCT03692910Phase 2Completed

A 2-Part Study (Open-label Followed by Double-blind, Randomized, Placebo-controlled, Parallel Group) of the Safety, Tolerability, Pharmacokinetics, and Efficacy of SAGE-217 in the Treatment of Subjects With Bipolar I/II Disorder With a Current Major Depressive Episode

Biogen·interventional·Posted Oct 2, 2018·Updated Dec 13, 2023

In Brief

A Phase 2 clinical trial evaluating SAGE-217 and Placebo for Bipolar Disorder I and 2 related conditions. Completed, enrolled 35 participants across 11 sites.

Detailed Summary

This is an open-label study evaluating the safety, tolerability, pharmacokinetics, and efficacy of SAGE-217 in the treatment of participants with bipolar I/II disorder with a current major depressive episode.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedOct 2, 2018
Enrollment StartAug 23, 2018
Primary CompletionMay 21, 2019
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 7.8 years ago

Interventions

SAGE-217drug

SAGE-217 capsule

Placebodrug

SAGE-217 matching placebo capsule