CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 3,733 enrolled
Drug / intervention
kit for self-diagnosis and self-treatmentother
Likely dose
Not stated in record
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Search/NCT03695770
NCT03695770N/ACompleted

Evaluation of a New Malaria Control Strategy Amongst Gold Miners Working Illegally in French Guiana (Malakit)

Centre Hospitalier de Cayenne·interventional·Posted Oct 4, 2018·Updated May 20, 2021

In Brief

A clinical study evaluating kit for self-diagnosis and self-treatment for Malaria and Public Health. Completed, enrolled 3,733 participants across 2 sites in 2 countries.

Detailed Summary

Illegal gold miners in French Guiana, a French overseas territory ('département') located in Amazonia, often carry malaria parasites (up to 46.8%). While the Guiana Shield Region aims at malaria elimination, the high prevalence of Plasmodiumin this hard-to-reach population in conjunction with frequent incorrect use of artemisinin-based anti-malarials could favor the emergence of resistant parasites. Due to geographical and regulatory issues in French Guiana, usual malaria control strategies cannot be implemented in this particular context.Therefore, new strategies targeting this specific population in the forest are required. Numerous discussions among health institutions and scientific partners from French Guiana, Brazil and Suriname have led to an innovative project based on the distribution of kits for self-diagnosis and self-treatment of Plasmodium infections. The kit-distribution will be implemented at "resting sites", which are areas across the border of French Guiana regularly frequented by gold miners. The main objective is to increase the appropriate use and complete malaria treatment after a positive malaria diagnosis with a rapid test, which will be evaluated with before-and-after cross-sectional studies. Monitoring indicators will be collected from health mediators at the time of kit distribution and during subsequent visits, and from illegal gold miners themselves, through a smartphone application. The project funding is multisource, including Ministries of Health of the three countries, WHO/PAHO, and the European Union.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBrazil, Suriname

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedOct 4, 2018
Enrollment StartApr 16, 2018
Primary CompletionMar 30, 2020
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 7.7 years ago

Interventions

kit for self-diagnosis and self-treatmentother

distribution of kits for malaria self-diagnosis and self-treatment after a training by health facilitators