CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 174 enrolled
Drug / intervention
Patidegib Topical Gel, 2% +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03703310
NCT03703310Phase 3Completed

A Multicenter, Randomized, Double-blind, Vehicle-controlled, Phase 3 Efficacy and Safety Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas (BCCs) in Subjects With Basal Cell Nevus Syndrome

Sol-Gel Technologies, Ltd.·interventional·Posted Oct 11, 2018·Updated Jul 3, 2024

In Brief

A Phase 3 clinical trial evaluating Patidegib Topical Gel, 2% and Patidegib Topical Gel, Vehicle for Basal Cell Nevus Syndrome. Completed, enrolled 174 participants across 49 sites in 10 countries.

Detailed Summary

This is a global, multicenter, randomized, double-blind, stratified, vehicle-controlled study of the efficacy and safety of Patidegib Topical Gel, 2%, applied topically twice daily to the face of adult participants with Gorlin syndrome. Participants will be required to apply the investigational product for 12 months. The primary endpoint is a comparison between the two treatment arms of the number of new BCCs that develop over the 12 month period.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBelgium, Canada, Denmark, France, Germany, Italy, Netherlands, Spain, United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20192020202120222023202420252026
First PostedOct 11, 2018
Enrollment StartFeb 19, 2019
Primary CompletionDec 28, 2020
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 7.7 years ago

Interventions

Patidegib Topical Gel, 2%drug

Patidegib Topical Gel, 2%

Patidegib Topical Gel, Vehicledrug

Patidegib Topical Gel, Vehicle