CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 1,074 enrolled
Drug / intervention
EVAC-PU-ETT +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03705286
NCT03705286Phase 2Completed

Randomized Trial of Endotracheal Tubes to Prevent Ventilator-Associated Pneumonia - PreVent 2 Study

Yale University·interventional·Posted Oct 15, 2018·Updated Sep 24, 2024

In Brief

A Phase 2 clinical trial evaluating EVAC-PU-ETT and PVC-ETT for Ventilator-acquired Pneumonia. Completed, enrolled 1,074 participants across 1 site.

Detailed Summary

Researchers are looking at two different types of breathing tubes to see if one is better than the other at preventing pneumonia. One of the tubes has a design features to prevent leakage of fluids from the mouth and the back of the throat into the lower airways and lungs. This is important since leakage of small amounts of fluid into the lungs may lead to pneumonia. The other tube is the standard tube used at most hospitals. The hypothesis is that the use of a breathing tube that reduces fluid leakage into the lungs will reduce the risk of developing pneumonia and improve quality of life and cognitive function, compared to the standard tube. The study will also look at the safety of the modified breathing tube, compared to the standard tube.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedOct 15, 2018
Enrollment StartMay 6, 2019
Primary CompletionFeb 23, 2023
TodayJul 2, 2026
Enrollment to primary: 3.8 yearsPosted 7.7 years ago

Interventions

EVAC-PU-ETTdevice

Placement of a EVAC-PU-ETT in the setting of emergent intubation.

PVC-ETTdevice

Placement of a PVC-ETT in the setting of emergent intubation.