CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 16 enrolled
Drug / intervention
Study Armother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03707054
NCT03707054N/ACompleted
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Correlation Between Vasopressin and Renal Function Following a Controlled Intraabdominal Pressure Elevation

The Cleveland Clinic·interventional·Posted Oct 16, 2018·Updated Apr 29, 2026

In Brief

A clinical study evaluating Study Arm for Intracranial Pressure Increase and Abdominal Compartment Syndrome. Completed, enrolled 16 participants across 1 site.

Detailed Summary

The aim of this study is to investigate any direct correlation between increased intrathoracic pressure, intraabdominal pressure and intracranial pressure, following a controlled elevation in intraabdominal pressure and intrathoracic pressure (PEEP). The second end-point is to investigate any correlation between elevated intracranial pressure and vasopressin release, urine output and urine and serum osmolality by measuring their values at different time-points.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsIntracranial Pressure Increase, Abdominal Compartment Syndrome
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedOct 16, 2018
Enrollment StartApr 28, 2017
Primary CompletionMay 28, 2024
Study CompletionDec 31, 2024
TodayJul 2, 2026
Enrollment to primary: 7.1 yearsPosted 7.7 years ago

Interventions

Study Armother

Measurements of optic nerve diameter, serum and urine osmolarity, serum vasopressin