CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 42 enrolled
Drug / intervention
Lactose free milk +3 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03713346
NCT03713346N/ACompleted

Comparing the Digestion of Milk With Different Beta-casein Protein Content by Dairy Intolerant Persons

Purdue University·interventional·Posted Oct 19, 2018·Updated Oct 8, 2021

In Brief

A clinical study evaluating Lactose free milk, Jersey milk, and 2 other interventions for Dairy Intolerance. Completed, enrolled 42 participants across 1 site.

Detailed Summary

Persons with dairy intolerance may experience cramps/abdominal pain, bloating, flatulence, acute diarrhea, or fecal urgency when they ingest excessive amounts of lactose. The intensity of these conditions can be mild or severe and likely depends on numerous variables including dose, transit time, intestinal residual lactase activity and microbiome potential to ferment lactose. Jersey cattle produce milk containing high levels of the A2 β-casein protein . There are claims that high A2 β-casein milk is more easily digested by people who are lactose maldigesters . We propose to conduct a double-blinded, randomized, controlled trial to determine if high A2 β-casein milk from Jersey cattle is actually better digested and tolerated by lactose maldigesters.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedOct 19, 2018
Enrollment StartJan 17, 2018
Primary CompletionSep 3, 2021
TodayJul 2, 2026
Enrollment to primary: 3.6 yearsPosted 7.7 years ago

Interventions

Lactose free milkother

Single dose of lactose free milk

Jersey milkother

Single dose of jersey milk

High A1 β-casein milkother

Single dose of high A1 β-casein milk (commercial milk)

High A2 β-casein milkother

Single dose of A2 β-casein milk