CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 150 enrolled
Drug / intervention
Pembrolizumabdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03715205
NCT03715205Phase 4Completed

A Prospective, Open-label, Phase 4 Study to Evaluate the Safety of Pembrolizumab (KEYTRUDA®) in Subjects With Unresectable or Metastatic Melanoma or PD-L1 Positive Non-small Cell Lung Cancer (NSCLC) in India (Keynote-593)

Merck Sharp & Dohme LLC·interventional·Posted Oct 23, 2018·Updated Aug 29, 2025

In Brief

A Phase 4 clinical trial evaluating Pembrolizumab for Carcinoma, Non-Small-Cell Lung and Melanoma. Completed, enrolled 150 participants across 8 sites.

Detailed Summary

This study has been designed to evaluate the safety of pembrolizumab in participants in India with unresectable or metastatic melanoma and participants with non-small cell lung cancer (NSCLC) who are either untreated (programmed cell death ligand 1 \[PD-L1\] ≥50%) or have experienced disease progression after a platinum-containing systemic therapy (PD-L1 ≥1%).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesIndia
Collaborators--

Timeline

Phase 4CompletedFinished
20192020202120222023202420252026
First PostedOct 23, 2018
Enrollment StartJan 31, 2019
Primary CompletionAug 21, 2024
TodayJul 2, 2026
Enrollment to primary: 5.6 yearsPosted 7.7 years ago

Interventions

Pembrolizumabdrug

Administered as an intravenous (IV) infusion every 3 weeks (Q3W)