CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 870 enrolled
Drug / intervention
Physiologic pacing device implantdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03719040
NCT03719040N/ACompleted

Physiologic Pacing Registry

Abbott Medical Devices·observational·Posted Oct 25, 2018·Updated Aug 19, 2024

In Brief

An observational study evaluating Physiologic pacing device implant for Bradycardia and 6 related conditions. Completed, enrolled 870 participants across 50 sites in 16 countries.

Detailed Summary

The Physiologic Pacing Registry is a prospective, observational, multi-center registry performed to gain a broader understanding of 1) physiologic pacing implant and follow-up workflows, including pacing and sensing measurements and 2) the clinical utility in creating a 3-dimensional electro-anatomical map of cardiac structures prior to physiologic pacing device implants based on the clinical site's routine care.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Austria, Canada, Czechia, France, Germany, Hong Kong, India, Italy, Netherlands, Poland, Singapore, South Africa, Spain, Switzerland, United States
Collaborators--

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedOct 25, 2018
Enrollment StartNov 27, 2018
Primary CompletionOct 7, 2021
TodayJul 2, 2026
Enrollment to primary: 2.9 yearsPosted 7.7 years ago

Interventions

Physiologic pacing device implantdevice

An alternative and potentially more effective pacing strategy for patients with electrical conduction abnormalities is physiologic pacing. Physiologic pacing is achieved by delivering a pacing stimulus to a cardiac conduction structure, such as the bundle of His or left bundle branch (LBB) of the His-Purkinje system, with a permanent lead. Physiologic pacing activates the heart through the native His-Purkinje conduction system, thus offering the most physiologic pacing approach to correct electrical dyssynchrony. Physiologic pacing has emerged as a feasible and safe alternative to pacemaker therapy and CRT with clinical and electrophysiological advantages.