CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 46 enrolled
Drug / intervention
Cognitive Training + fMRIbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03720821
NCT03720821N/ACompleted
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Cognitive Flexibility Training for Persistent Pain: Neuroimaging Pilot (COFLEX-i)

Washington University School of Medicine·interventional·Posted Oct 25, 2018·Updated Apr 13, 2022

In Brief

A clinical study evaluating Cognitive Training + fMRI for Chronic Pain and 3 related conditions. Completed, enrolled 46 participants across 1 site.

Detailed Summary

To determine whether a 5-week computer-based cognitive training intervention results in changes in resting-state functional connectivity (rsFC) within the brain networks.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsChronic Pain, Knee Pain Chronic, Hip Pain Chronic, Back Pain
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedOct 25, 2018
Enrollment StartJul 16, 2019
Primary CompletionJun 30, 2021
Study CompletionFeb 25, 2022
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 7.7 years ago

Interventions

Cognitive Training + fMRIbehavioral

Consented subjects will be asked to participate in the study for up to five months. Patients will be consented at the Washington University Department of Anesthesiology and will be asked to complete baseline resilience, pain, and anxiety and depression questionnaires, along with cognitive tests by pencil and paper that will be administered by a member of the research team. The participants will also be required to complete a computer-based Trails-making test, Color Match test, and NCPT (Neurocognitive Performance Test) battery at baseline, and undergo a functional magnetic resonance imaging (fMRI) session. All subjects will be asked to complete the three paper-pencil and computer-based measurements along with repeat pain questionnaire again 1-3 days after completion of training, undergo a second fMRI scan at that time, and complete the questionnaires again 3 months after the completion of training.