CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 61 enrolled
Drug / intervention
High Flow High Humidity device +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03721419
NCT03721419N/ACompleted

Low-Flow (LF) Oxygen Versus Heated Humidified High-Flow (HF) Therapy Following Tracheostomy

Barnes-Jewish Hospital·interventional·Posted Oct 26, 2018·Updated Jul 20, 2021

In Brief

A clinical study evaluating High Flow High Humidity device and Low Flow High Humidity device for Acute Respiratory Failure. Completed, enrolled 61 participants across 1 site.

Detailed Summary

Respiratory failure patients sometimes receive tracheostomy due to difficulty weaning from mechanical ventilation. Efforts to wean patients with a tracheostomy usually involve the administration of oxygen via High Humidity device. There are two major ways of administering oxygen to patients which include low flow delivered at less than 10Liters per minute (LPM) and high-flow delivered at greater than 10LPM. There is not a currently accepted standard of care practice for how to administer oxygen therapy to these patients. Both Low and High Flow are accepted practices in the US.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedOct 26, 2018
Enrollment StartMay 17, 2018
Primary CompletionMar 30, 2020
Study CompletionApr 7, 2020
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 7.7 years ago

Interventions

High Flow High Humidity devicedevice

High Flow High Humidity device has a flow generator built into the body of unit and can deliver flows between 10 to 60 Liters per minute (LPM) with oxygen bled in as needed in order to deliver specified Fraction of inspired Oxygen (FiO2)

Low Flow High Humidity devicedevice

Standard high humidity trach collar utilizing venturi device bleed in