CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 80 enrolled
Drug / intervention
Propolis +1 moredrug
Likely dose
Calcium Hydroxide 150 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03723980
NCT03723980Phase 3Completed
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Effect of Propolis Paste as Intracanal Medicament on Post-Endodontic Pain: a Double-Blind Randomized Clinical Trial.

Juzer Shabbir Saifee·interventional·Posted Oct 30, 2018·Updated Jun 6, 2019

In Brief

A Phase 3 clinical trial evaluating Propolis and Calcium Hydroxide for Pain, Postoperative. Completed, enrolled 80 participants across 1 site.

Detailed Summary

This study evaluates the role of propolis paste as compared to calcium hydroxide (when used as intracanal medication) in prevention and treatment of pain after root canal treatment in necrotic (infected) teeth. Half of the participants will receive calcium hydroxide, while the other half will receive propolis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain, Postoperative
CountriesPakistan
CollaboratorsDow University of Health Sciences

Timeline

Phase 3CompletedFinished
201820192020202120222023202420252026
First PostedOct 30, 2018
Enrollment StartNov 16, 2017
Primary CompletionApr 24, 2018
Study CompletionOct 15, 2018
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 7.7 years ago

Interventions

Propolisdrug

it is a natural product obtained from beehive. it has been evaluated for biocompatibility and toxicity; and it is found that it is extremely biocompatible material. In our study, propolis powder will be mixed with saline in a ratio of 1 : 1.5 (propolis powder(wt) / saline(vol)) to form paste; and inserted into the root canals. it will be inserted once and will remain in root canals for 4 days.

Calcium Hydroxidedrug

it is a synthetic antimicrobial intracanal medicament and gold standard to which other medicaments are being compared. approximately 150 mg of calcium hydroxide paste will be inserted in the root canal. it will be inserted only once and will remain in root canals for 4 days.