At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Clinical Effects of Doxycycline in the Treatment of Aggressive Periodontitis: Comparative Clinical Study
In Brief
A Phase 2 clinical trial evaluating amoxicillin plus metronidazole and Doxycycline for Aggressive Periodontitis. Completed, enrolled 24 participants across 1 site.
Detailed Summary
The aim of the study was to compare the clinical effects of systemic use of doxycycline to amoxicillin plus metronidazole as adjunctive treatment in nonsurgical debridement of aggressive periodontitis (AgP). Twenty four patients with aggressive periodontitis were enrolled in this clinical study. They all received oral hygiene instruction and full-mouth nonsurgical debridement using manual instruments. The test group received as adjunctive antibiotic treatment 200 mg of doxycycline the first day followed by 100 mg per day during 14 days. The control group received 500 of amoxicillin and 250 of metronidazole, three times a day for 7 days.
Study Details
Timeline
Interventions
patients were administered 250 mg of Flagyl and 500 mg of Dyspamox, three times a day for 7 days
patients were administered 200 mg of Longamycine the first day and 100 mg per day for 14 days