CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 149 enrolled
Drug / intervention
Trophic Nutritionprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

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Search/NCT03728452
NCT03728452N/ACompleted

Trophic Nutrition in Patients Submitted to High Flow Oxygen Therapy and / or Non Invasive

Hospital San Carlos, Madrid·observational·Posted Nov 2, 2018·Updated May 24, 2024

In Brief

An observational study evaluating Trophic Nutrition for Noninvasive Ventilation and Trophic Nutrition. Completed, enrolled 149 participants across 1 site.

Detailed Summary

The decision about the initiation of enteral nutrition therapy in critically ill patients with oxygen therapy needs with HFC and / or NIMV is a matter of debate at present. Despite the benefits associated with this practice in critically ill patients, the scarcity of clinical studies in patients with sufficient methodological quality, as well as the absence of specific recommendations on enteral nutrition therapy in this type of patient, generates controversy in the professionals involved in critical patient care.

Study Details

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedNov 2, 2018
Enrollment StartJan 1, 2019
Primary CompletionAug 1, 2023
Study CompletionFeb 1, 2024
TodayJul 2, 2026
Enrollment to primary: 4.6 yearsPosted 7.7 years ago

Interventions

Trophic Nutritionprocedure

According to previously published studies of Trophic Nutritions in critically ill patients, an energy goal of 20-30% estimated caloric needs of 20-30 kcal / kg and a protein intake of 1.2 to 2.0 g / kg / day of proteins will be established. at most 72 hours after the start of nutritional therapy. The rhythm of initiation and increase of enteral contributions will be at the discretion of each participating ICU. Prokinetic or parenteral nutrition (PN) complementary will not be used routinely, leaving its indication at the discretion of the responsible physician. A hyperproteic nutritional formula (10 g / 100 ml) will be used, with a caloric intake of 1.2 kcal / ml and a non-protein kcal / nitrogen ratio of 52: 1. TN will be administered over 23 hours each day by continuous infusion pump. The head of the patient's bed will rise above 30° as much as possible to reduce the risk of aspiration. The Gastric Residue Volume (GRV) will be measured every 24 hours.