CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 405 enrolled
Drug / intervention
Volatile agent +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03729011
NCT03729011Phase 4Completed
CompareCT.gov

Delirium Reduction by Volatile Anesthesia in Cardiac Surgery: Prospective, Randomized, Single-blinded Study

Meshalkin Research Institute of Pathology of Circulation·interventional·Posted Nov 2, 2018·Updated May 15, 2025

In Brief

A Phase 4 clinical trial evaluating Volatile agent and Propofol for Delirium. Completed, enrolled 405 participants across 5 sites.

Detailed Summary

Parallel group, prospective, randomized, controlled, single-blinded trial. The aim of our study is to test the hypothesis that volatile anesthesia would reduce the incidence of early postoperative delirium in patients undergoing cardiac surgery with CPB as compared to TIVA.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDelirium
CountriesRussia
Collaborators--

Timeline

Phase 4CompletedFinished
20192020202120222023202420252026
First PostedNov 2, 2018
Enrollment StartJan 9, 2019
Primary CompletionJan 11, 2024
TodayJul 2, 2026
Enrollment to primary: 5.0 yearsPosted 7.7 years ago

Interventions

Volatile agentdrug

Patients will receive volatile agent to provide general anaesthesia, including CPB period. Volatile agents will be administered from anesthesia induction to the end of surgery. Concentration (MAC) of volatile agent will be selected by anaesthesiologist according to clinical situation and patient features.

Propofoldrug

Patients will receive propofol and no volatile agent. Propofol will be used for induction and maintenance of anesthesia.