CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 55 enrolled
Drug / intervention
CA-008 +1 moredrug
Likely dose
CA-008 5 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03731364
NCT03731364Phase 2Completed

A Phase 2, Randomized, Double-blind, Placebo-Controlled Efficacy, Pharmacokinetics and Safety Study of CA-008 (Vocacapsaicin) in Subjects Undergoing Total Knee Arthroplasty

Concentric Analgesics·interventional·Posted Nov 6, 2018·Updated Feb 15, 2022

In Brief

A Phase 2 clinical trial evaluating CA-008 and Placebo for Postsurgical Pain. Completed, enrolled 55 participants across 1 site.

Detailed Summary

This is a two-part, Phase 2, multi-center, randomized, double-blind, placebo-controlled, parallel design study of CA-008 (vocacapsaicin) vs. placebo injected/instilled during an elective TKA.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedNov 6, 2018
Enrollment StartOct 29, 2018
Primary CompletionApr 30, 2019
Study CompletionMay 31, 2019
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 7.7 years ago

Interventions

CA-008drug

5 mg CA-008 (0.05 mg/mL), 10 mg CA-008 (0.1 mg/mL) and 15 mg CA-008 (0.15 mg/mL)

Placebodrug

Placebo