CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 86 enrolled
Drug / intervention
Rilonacept +1 moredrug
Likely dose
Rilonacept 320 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03737110
NCT03737110Phase 3Completed

Phase 3, Double-Blind, Placebo-Controlled, Randomized Withdrawal Study With Open-label Extension, to Assess the Efficacy and Safety of Rilonacept Treatment in Subjects With Recurrent Pericarditis

Kiniksa Pharmaceuticals (UK), Ltd.·interventional·Posted Nov 9, 2018·Updated Sep 6, 2023

In Brief

A Phase 3 clinical trial evaluating Rilonacept and Placebo for Recurrent Pericarditis. Completed, enrolled 86 participants across 21 sites in 4 countries.

Detailed Summary

The primary objective of this study was to assess the efficacy of rilonacept treatment in participants with recurrent pericarditis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Israel, Italy, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20192020202120222023202420252026
First PostedNov 9, 2018
Enrollment StartJan 7, 2019
Primary CompletionMay 29, 2020
Study CompletionJun 30, 2022
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 7.6 years ago

Interventions

Rilonaceptdrug

Rilonacept 320 mg (or 4.4 mg/kg in pediatric participants ≥12 and \<18 years old) SC , followed by 160 mg (or 2.2 mg/kg in pediatric participants ≥12 and \<18 years old) injections once weekly

Placebodrug

Placebo SC injections once weekly