CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 49 enrolled
Drug / intervention
AR-1105-CF1 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03739593
NCT03739593Phase 2Completed

A Multicenter, Open-label, Safety and Proof-of-concept Study to Assess Safety, Tolerability and Efficacy of AR-1105 in Subjects With Macular Edema Due to Retinal Vein Occlusion (RVO)

Aerie Pharmaceuticals·interventional·Posted Nov 14, 2018·Updated Feb 28, 2022

In Brief

A Phase 2 clinical trial evaluating AR-1105-CF1 and AR-1105-CF2 for Macular Edema. Completed, enrolled 49 participants across 11 sites.

Detailed Summary

This study will evaluate the safety, tolerability and efficacy of AR-1105 (dexamethasone implant) for the treatment of macular edema (ME) due to retinal vein occlusion (RVO). A more durable intravitreal implant containing a low dose of dexamethasone may result in less frequent retreatments, and potentially lower the incidence of steroid-related side effects without compromising efficacy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMacular Edema
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedNov 14, 2018
Enrollment StartMar 13, 2019
Primary CompletionMay 14, 2020
Study CompletionJul 9, 2020
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 7.6 years ago

Interventions

AR-1105-CF1drug

AR-1105 clinical formulation 1 (AR-1105-CF1)

AR-1105-CF2drug

AR-1105 clinical formulation 2 (AR-1105-CF2)