CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 136 enrolled
Drug / intervention
Quadratus Lumborum Block +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03745794
NCT03745794Phase 2Completed
CompareCT.gov

Randomized Controlled Trial of Repeat vs. Single Quadratus Lumborum Block to Reduce Opioid Prescriptions After Open Pancreatectomy ("RESQU-BLOCK" Trial)

M.D. Anderson Cancer Center·interventional·Posted Nov 19, 2018·Updated Dec 23, 2025

In Brief

A Phase 2 clinical trial evaluating Best Practice, Quadratus Lumborum Block, and 2 other interventions for Pancreatic Carcinoma. Completed, enrolled 136 participants across 1 site.

Detailed Summary

This phase II trial studies how an additional anesthetic nerve block, called a quadratus lumborum block, works to reduce the need for opioids in patients after pancreatic surgery. Giving an additional regional anesthetic after surgery may hasten the weaning process, reduce the need for opioid medications upon discharge, and reduce the risk of opioid dependence.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPancreatic Carcinoma
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedNov 19, 2018
Enrollment StartFeb 28, 2019
Primary CompletionJul 31, 2025
TodayJul 2, 2026
Enrollment to primary: 6.4 yearsPosted 7.6 years ago

Interventions

Best Practiceother

Given standard of care

Quadratus Lumborum Blockdrug

Undergo QL block

Quality-of-Life Assessmentother

Ancillary studies

Questionnaire Administrationother

Ancillary studies