CI

At a glance

ClinicalIndex Comparison Record
N/ARecruiting· 90 target
Drug / intervention
Stereotactic Ablative Radiotherapyradiation
Likely dose
Not stated in record
Key inclusion· 3
  • Solid kidney mass (primary RCC or metastasis) amenable to SABR ≤6cm
  • Histological or radiological diagnosis of renal tumor
  • Inoperable due to high surgical risk or patient declined surgery
Key exclusion· 5
  • ≥5 active metastases
  • Systemic therapy (except endocrine therapy) within 60 days prior to SABR
  • Prior abdominal radiotherapy with field overlap resulting in excessive kidney doses
  • End stage renal failure > stage 4 (KDOQI guidelines)

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03747133
NCT03747133N/ARecruitingOn Track
Long Recruiting

Phase II Study: Stereotactic Ablative Radiotherapy for Renal Tumors

University Health Network, Toronto·interventional·Posted Nov 20, 2018·Updated Jun 4, 2026

In Brief

A clinical study evaluating Stereotactic Ablative Radiotherapy for Renal Tumor. Currently recruiting, targeting 90 participants across 1 site.

Detailed Summary

Renal Cell Carcinoma (RCC) is the most common type of kidney cancer. The usual treatment for this type of cancer is surgery. Considering the most common patients are an average age of 65 and some are not suitable candiates for surgery, there is great interest in non-surgical alternatives for kidney cancer treatments. This study will investigate the use of Stereotactic Ablative Radiosurgery (SABR) for renal tumors. SABR is a non-invasive alternative, which involves delivery of high doses of radiation to the target, while minimizing the risk of injury to the surrounding organs. Patients will be seen before and end of treatmetn and will be followed at 4 month intervals for up to 2 years. During the follow ups, patients will be asked to complete a quality of life questionnaire and will have standard of care imaging.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRenal Tumor
CountriesCanada
Collaborators--

Timeline

N/ARecruiting
2019202020212022202320242025202620272028
First PostedNov 20, 2018
Enrollment StartNov 1, 2018
Primary CompletionNov 1, 2027
TodayJul 2, 2026
Enrollment to primary: 9 yearsPosted 7.6 years agoPrimary completion in 1.3 years

Interventions

Stereotactic Ablative Radiotherapyradiation

Stereotactic Ablative Radiotherapy to renal tumors with a dose of 27.5-40 Gy in 5 fractions.