CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 5,421 enrolled
Drug / intervention
Adherence Interventionother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03748420
NCT03748420N/ACompleted

A Team-Based and Technology-Driven Adherence Intervention to Improve Chronic Disease Outcomes

HealthPartners Institute·interventional·Posted Nov 20, 2018·Updated Feb 26, 2024

In Brief

A clinical study evaluating Adherence Intervention for Hyperlipidemia and 3 related conditions. Completed, enrolled 5,421 participants across 1 site.

Detailed Summary

More than 50% of adults treated for diabetes, hypertension, or lipid disorders have suboptimal medication adherence, a prominent barrier to continued improvement in chronic disease care in the United States. Primary care providers (PCPs) often fail to identify medication nonadherence and/or have insufficient time and training to address underlying reasons for it. In this project, we propose a patient-centered and technology-driven strategy to identify patients with adherence issues and apply a team approach to help them achieve evidence-based personalized goals for glucose, blood pressure, or lipids. This intervention extends the use of a widely available clinical decision support (CDS) infrastructure to support a model of care that, for the first time outside of a fully integrated care environment, will integrate pharmacists within the primary care team. The intervention relies on a continuous health informatics loop to do the following: (a) identify high-risk patients with adherence problems at the point of care by expanding the capability of an electronic medical record (EMR)-linked CDS to identify poor adherence to medications; (b) establish and maintain an auto-populating up-to-date registry of patients identified for proactive pharmacist outreach; (c) implement a pharmacist outreach strategy based on an information-motivation-behavioral (IMB) framework recommended by the World Health Organization (WHO) with demonstrated ability to influence adherence across a variety of clinical applications; and (d) coordinate care and adherence information by incorporating pharmacist assessment and action plans into CDS at subsequent office encounters.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedNov 20, 2018
Enrollment StartAug 19, 2020
Primary CompletionOct 25, 2022
Study CompletionJan 31, 2023
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 7.6 years ago

Interventions

Adherence Interventionother

The adherence enhanced intervention consists of clinical decision support related to cardiovascular risk factors enhanced with external medication adherence information and is delivered at the point of care to the healthcare provider and patient.