CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 50 enrolled
Drug / intervention
BI 1358894 +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03754959
NCT03754959Phase 1Completed

Safety, Tolerability, and Pharmacokinetics of Multiple Rising Oral Doses of BI 1358894 (Double-blind, Randomised, Placebo-controlled, Parallel-group Design) and Evaluation of Midazolam Interaction (Nested, Open, Fixed-sequence, Intra-individual Comparison) in Healthy Male Subjects

Boehringer Ingelheim·interventional·Posted Nov 27, 2018·Updated Apr 3, 2025

In Brief

A Phase 1 clinical trial evaluating BI 1358894, Placebo, and 1 other intervention for Healthy. Completed, enrolled 50 participants across 1 site.

Detailed Summary

The primary objective of the trial is to investigate the safety and tolerability of BI 1358894 in healthy male subjects following oral administration of multiple rising doses over 14 days.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesGermany
Collaborators--

Timeline

Phase 1CompletedFinished
20192020202120222023202420252026
First PostedNov 27, 2018
Enrollment StartDec 18, 2018
Primary CompletionJul 22, 2019
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 7.6 years ago

Interventions

BI 1358894drug

Film-coated tablet

Placebodrug

Film-coated tablet

Midazolamdrug

Solution for injection