CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 40 enrolled
Drug / intervention
Citicolinedietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03758118
NCT03758118N/ACompleted

Neuroprotection and Neuroenhancement in a Model of Optic Nerve Neurodegeneration (Non Arteritic Ischemic Optic Neuropathy): Study of Morpho-functional Changes Related to Treatment With Citicoline Oral Solution

Fondazione G.B. Bietti, IRCCS·interventional·Posted Nov 29, 2018·Updated Nov 24, 2023

In Brief

A clinical study evaluating Citicoline for Non-arteritic Ischemic Optic Neuropathy. Completed, enrolled 40 participants across 1 site.

Detailed Summary

The investigators tested the hypothesis whether the treatment with Citicoline in oral solution (OS-Citicoline) would increase or stabilize visual acuity, retinal ganglion cells (RGCs) function and neural conduction along the visual pathways (neuroenhancement), and/or induce preservation of RGCs fibers' loss (neuroprotection) in an human model of neurodegeneration: non-arteritic ischemic optic neuropathy (NAION).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesItaly
Collaborators--

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedNov 29, 2018
Enrollment StartFeb 20, 2017
Primary CompletionJul 25, 2017
Study CompletionApr 25, 2018
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 7.6 years ago

Interventions

Citicolinedietary

Citicoline administered in oral solution