CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 50 enrolled
Drug / intervention
Enhanced Problem-Solving Training (E-PST) +2 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03759223
NCT03759223N/ACompleted

Enhanced Problem-Solving Training (E-PST) to Improve Recovery From mTBI

VA Office of Research and Development·interventional·Posted Nov 29, 2018·Updated Aug 27, 2024

In Brief

A clinical study evaluating Enhanced Problem-Solving Training (E-PST), Healthy Living Messages (HLM), and 1 other intervention for Brain Concussion. Completed, enrolled 50 participants across 1 site.

Detailed Summary

Mild traumatic brain injury (mTBI) is among the most common injuries sustained by Veterans of Operations Enduring and Iraqi Freedom. It is also highly co-morbid with mental health conditions, such as post-traumatic stress disorder and depression. While mTBI alone is not typically thought to cause lasting deficits in personal functioning or cognitive abilities, Veterans with a history of mTBI nonetheless report chronic psychological distress, as well as subjective difficulties with attention, concentration, poor frustration tolerance, and decision-making. Although current clinical practice guidelines for mTBI emphasize primary care-based symptom management, there are presently no evidence-based interventions to treat mental health symptoms in this setting. This research proposal therefore seeks to adapt and pilot test a brief, primary care-based intervention (E-PST) to reduce psychological distress in Veterans with mTBI by augmenting problem-solving skills, and helping them to develop specific cognitive and behavioral skills to improve upon their self-reported cognitive inefficiencies. The investigators hypothesize that Veterans who complete E-PST will report improvements in psychological distress compared to participants in the control condition.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedNov 29, 2018
Enrollment StartOct 1, 2019
Primary CompletionJun 7, 2023
TodayJul 2, 2026
Enrollment to primary: 3.7 yearsPosted 7.6 years ago

Interventions

Enhanced Problem-Solving Training (E-PST)behavioral

E-PST is a combined treatment that is comprised of brief problem-solving training and compensatory cognitive skills training. Randomized participants were assigned 1:1 to E-PST or HLM.

Healthy Living Messages (HLM)behavioral

Healthy Living Messages are primary care-congruent messages that consist of simple advice regarding general health behaviors and preventive care. Randomized participants were assigned 1:1 to E-PST or HLM.

Enhanced Problem-Solving Training (E-PST) (non-randomized)behavioral

E-PST is a combined treatment that is comprised of brief problem-solving training and compensatory cognitive skills training. Non-randomized participants were assigned to E-PST only.