CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 18 enrolled
Drug / intervention
CDT with Negative Pressure +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03760744
NCT03760744N/ACompleted

Imaging Biomarkers of Lymphatic Dysfunction

Vanderbilt University Medical Center·interventional·Posted Nov 30, 2018·Updated Oct 16, 2025

In Brief

A clinical study evaluating CDT with Negative Pressure and CDT alone for Secondary Lymphedema. Completed, enrolled 18 participants across 1 site.

Detailed Summary

Persons with secondary arm and/or upper quadrant lymphedema following cancer therapies commonly are prescribed complete decongestive therapy as a course of management of their lymphedema. The investigators will perform a repeated-measures cross-over trial to test the hypothesis that mobilization of protein enriched hardened tissue using graded negative pressure therapy in conjunction with complete decongestive therapy (CDT) is more effective to standard CDT alone for secondary lymphedema management.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedNov 30, 2018
Enrollment StartJan 23, 2019
Primary CompletionMar 15, 2025
TodayJul 2, 2026
Enrollment to primary: 6.1 yearsPosted 7.6 years ago

Interventions

CDT with Negative Pressureprocedure

Complete decongestive therapy (physical therapy conservative intervention of compression, manual lymphatic drainage, skin care and exercises) in conjunction with manual intervention of graded negative pressure application for lymphatic stimulation/ tissue clearance

CDT aloneprocedure

Complete decongestive therapy (physical therapy conservative intervention of compression, manual lymphatic drainage, skin care and exercises) for lymphatic stimulation/ tissue clearance