CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 51 enrolled
Drug / intervention
5% Fluoride Varnish +2 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03770286
NCT03770286N/ACompleted
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Treatment of Interproximal Carious Lesions on Primary Molar Teeth With SDF and Super Floss Application Versus SDF Without Super Floss Versus Fluoride Varnish Alone: a Pilot Phase 3 Randomized Controlled Trial

Children's Hospital Los Angeles·interventional·Posted Dec 10, 2018·Updated Oct 15, 2024

In Brief

A clinical study evaluating 5% Fluoride Varnish, 38% Silver diamine fluoride, and 1 other intervention for Dental Caries in Children and 2 related conditions. Completed, enrolled 51 participants across 1 site.

Detailed Summary

This study investigates whether 1) Silver diamine fluoride (SDF) application using Super Floss can arrest and/or reverse initial interproximal caries on primary molars and 2) whether SDF applied with Super Floss is more effective in arresting or remineralizing initial interproximal lesion in comparison to SDF applied without Super Floss or fluoride varnish applied alone.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDental Caries in Children, Dental Caries Class II, Dental Caries
CountriesUnited States
CollaboratorsUniversity of Southern California

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedDec 10, 2018
Enrollment StartJan 22, 2019
Primary CompletionMay 31, 2023
TodayJul 2, 2026
Enrollment to primary: 4.4 yearsPosted 7.6 years ago

Interventions

5% Fluoride Varnishdevice

Topical varnish

38% Silver diamine fluoridedevice

Topical varnish

Super Flossdevice

Floss will be used as a delivery agent of SDF to target interproximal carious lesion.