CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 100 enrolled
Drug / intervention
Emtricitabine / Tenofovir Disoproxil Oral Tablet +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03771638
NCT03771638Phase 4Completed
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DOT Diary Longitudinal Pilot: A Mobile App for Pre-Exposure Prophylaxis Adherence in Young Men

Public Health Foundation Enterprises, Inc.·interventional·Posted Dec 11, 2018·Updated Jul 3, 2025

In Brief

A Phase 4 clinical trial evaluating Emtricitabine / Tenofovir Disoproxil Oral Tablet and DOT Diary mobile app for Adherence, Medication and 3 related conditions. Completed, enrolled 100 participants across 2 sites.

Detailed Summary

The researchers are working with a technology company, AiCure, to develop a smartphone app, DOT Diary, which combines two drug adherence strategies. DOT Diary reminds people when it is time to take their medication, and uses motion-sensing technology to visually and automatically confirm the pill was swallowed. The goal of this study is to assess the impact of the app on adherence to HIV pre-exposure prophylaxis (PrEP) for the prevention of HIV.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAdherence, Medication, Risk Behavior, Pre-Exposure Prophylaxis, HIV Prevention
CountriesUnited States
CollaboratorsNational Institute of Mental Health (NIMH), San Francisco Department of Public Health, Emory University, AiCure

Timeline

Phase 4CompletedFinished
20192020202120222023202420252026
First PostedDec 11, 2018
Enrollment StartFeb 1, 2019
Primary CompletionApr 21, 2020
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 7.6 years ago

Interventions

Emtricitabine / Tenofovir Disoproxil Oral Tabletdrug

Open label daily emtricitabine/tenofovir disoproxil oral tablet

DOT Diary mobile appother

DOT Diary mobile application for tracking medication adherence and sexual activities.