CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 277 enrolled
Drug / intervention
Apremilast +1 moredrug
Likely dose
Apremilast 30 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03774875
NCT03774875Phase 4Completed

A Phase 4, Multi-center, Randomized, Double-blind, Placebo-controlled Study of the Impact of Apremilast (CC-10004) on Quality of Life, Efficacy, and Safety in Subjects With Manifestations of Plaque Psoriasis and Impaired Quality of Life

Amgen·interventional·Posted Dec 13, 2018·Updated Jul 10, 2025

In Brief

A Phase 4 clinical trial evaluating Apremilast and Placebo for Psoriasis. Completed, enrolled 277 participants across 72 sites in 6 countries.

Detailed Summary

The primary objective of the study is to assess the impact of treatment with apremilast 30 mg twice daily for 16 weeks, compared to placebo, on health-related quality of life (QOL) in adults with manifestations of plaque psoriasis and impaired quality of life.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPsoriasis
CountriesFrance, Germany, Italy, Spain, Switzerland, United Kingdom
Collaborators--

Timeline

Phase 4CompletedFinished
20192020202120222023202420252026
First PostedDec 13, 2018
Enrollment StartMar 28, 2019
Primary CompletionFeb 1, 2021
Study CompletionNov 3, 2021
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 7.6 years ago

Interventions

Apremilastdrug

Apremilast 30 mg tablets taken orally twice a day.

Placebodrug

Placebo tablets taken orally twice a day