CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 90 enrolled
Drug / intervention
Levobupivacaine +2 moredrug
Likely dose
Dexmedetomidine Injection [Precedex] 1 µgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03778671
NCT03778671Phase 2Completed
CompareCT.gov

Dexmedetomidine Versus Fentanyl Added to Levobupivacaine for Transversus Abdominis Plane (TAP) Block in Elderly Patients Undergoing Lower Abdominal Surgery

Assiut University·interventional·Posted Dec 19, 2018·Updated Oct 18, 2021

In Brief

A Phase 2 clinical trial evaluating Levobupivacaine, Dexmedetomidine Injection [Precedex], and 1 other intervention for Transversus Abdominis Block. Completed, enrolled 90 participants across 1 site.

Detailed Summary

The perioperative management of pain following lower abdominal surgery can pose a challenge to anesthesia providers. Conventional practice has involved the use of opioids as well as neuraxial analgesic techniques. Unfortunately, these therapies are not without potential risks and side effects. These include nausea, vomiting, pruritus, urinary retention, constipation, respiratory depression, and sedation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTransversus Abdominis Block
CountriesEgypt
Collaborators--

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedDec 19, 2018
Enrollment StartJan 1, 2019
Primary CompletionNov 1, 2019
Study CompletionDec 1, 2019
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 7.5 years ago

Interventions

Levobupivacainedrug

Patients will receive Levobupivacaine 5%

Dexmedetomidine Injection [Precedex]drug

Patients will receive Levobupivacaine 5% + 1 µg/kg dexmedetomedine

fentanyldrug

Patients will receive Levobupivacaine 5% + 1 µg/kg fentanyl