At a glance

ClinicalIndex Comparison Record

N/ACompleted· 50 enrolled

Drug / intervention

preoperative nutritiondietary

Likely dose

Not stated in record

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Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03793036

NCT03793036N/ACompleted

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A Randomized Controlled Study of Preoperative Oral Carbohydrate Loading Versus Fasting in Patients Undergoing Colorectal Surgery

Nermina Rizvanović·interventional·Posted Jan 4, 2019·Updated Jan 7, 2019

In Brief

A clinical study evaluating preoperative nutrition for Insulin Resistance and 3 related conditions. Completed, enrolled 50 participants across 1 site.

Detailed Summary

This study compared traditional concept of preoperative fasting before elective open colon surgery and preoperative treatment with carbohydrate oral drink in intention to improve postoperative stress response to surgical procedure. Hypothesis was: preoperative oral carbohydrate drink reduces postoperative insulin resistance, improves insulin sensitivity, reduces postoperative inflammatory response in terms of the value of Glasgow Prognostic Score (GPS) and IL-6, improves postoperative patient's subjective well-being and surgical clinical outcome.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsInsulin Resistance, Inflammatory Response, Exaggerated Well-Being, Length of Stay

CountriesBosnia and Herzegovina

Collaborators--

Timeline

N/ACompletedFinished

20192020202120222023202420252026

Enrollment StartMay 2018

Primary CompletionDec 2018

Study CompletionDec 2018

First PostedJan 2019

TodayJul 2026

First PostedJan 4, 2019

Enrollment StartMay 1, 2018

Primary CompletionDec 20, 2018

Study CompletionDec 31, 2018

TodayJul 2, 2026

Enrollment to primary: 8 monthsPosted 7.5 years ago

Interventions

preoperative nutritiondietary

The participants of experimental group received 400 mil of a clear carbohydrate drink (12,5 gr/100 mil carbohydrate, 50 kcal/100ml, pH 5.0) at 10:00 pm the evening before surgery and another 200 mil of the carbohydrate drink on the day of surgery, 2 hours before induction of anesthesia. After surgery the participants fasted until the recovery of function of the bowel.