CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 66 enrolled / 66 target
Drug / intervention
MINST +2 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03797807
NCT03797807N/ACompletedOn Track (0.8/mo)Completion was 6mo ago
CompareCT.gov

Clinical and Radiographic Changes in Intrabony Defects Following Non-surgical vs. Surgical Minimally-invasive Periodontal Therapy. A Parallel Group, Single Centre, Examiner-blind, Non-inferiority Randomised Controlled Trial

Queen Mary University of London·interventional·Posted Jan 9, 2019·Updated Jun 29, 2026

In Brief

A clinical study evaluating MINST, MIST, and 1 other intervention for Periodontitis. Completed, enrolled 66 participants across 1 site.

Detailed Summary

To compare the efficacy of a modified minimally-invasive non-surgical periodontal therapy (MINST) approach with a surgical approach (M-MIST) in determining bone and clinical attachment changes in intrabony defects

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPeriodontitis
CountriesUnited Kingdom
Collaborators--

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedJan 9, 2019
Enrollment StartMar 20, 2019
Primary CompletionDec 31, 2025
TodayJul 2, 2026
Enrollment to primary: 6.8 yearsPosted 7.5 years ago

Arms & Interventions

MINSTexperimental

Minimally invasive non surgical treatment

Procedure: MINST
MISTactive_comparator

Minimally invasive surgical treatment

Procedure: MIST
GTI + MINSTactive_comparator

Minimally invasive non surgical treatment + Geometric/Thermal Imaging (GTI subgroup)

Procedure: MINSTDiagnostic Test: GTI subgroup (Geometrical/Thermal Imaging)
GTI + MISTactive_comparator

Minimally invasive surgical treatment + Geometric/Thermal Imaging (GTI subgroup)

Procedure: MISTDiagnostic Test: GTI subgroup (Geometrical/Thermal Imaging)

Interventions

MINSTprocedure

A non-surgical minimally invasive treatment protocol, named MINST, has been proposed for the treatment of periodontal intrabony defects, in order to minimize patient discomfort and maximize the healing potential

MISTprocedure

A minimally invasive surgical treatment protocol, named MIST, has been proposed for the treatment of periodontal intrabony defects, in order to minimize patient discomfort and maximize the healing potential

GTI subgroup (Geometrical/Thermal Imaging)other

Geometrical/Thermal Imaging