CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 222 enrolled
Drug / intervention
Child-Parent Psychotherapy (CPP) +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03808987
NCT03808987N/ACompleted

TRANSFORM: Translational Research That Adapts New Science FOR Maltreatment Prevention

University of Rochester·interventional·Posted Jan 18, 2019·Updated May 14, 2026

In Brief

A clinical study evaluating Child-Parent Psychotherapy (CPP) and Community Health Worker (CHW) home visitation for Pregnant and Parenting Women. Completed, enrolled 222 participants across 1 site.

Detailed Summary

Home visitation by community health workers is a commonly utilized approach to support families and prevent child maltreatment. At times, however, more intensive intervention is needed to address familial trauma, depression, or other challenges. This preventive treatment evaluation study evaluates whether adding Child-Parent Psychotherapy (CPP) to a Community Health Worker (CHW) outreach model improves positive parenting and parent-child relationships above CHW alone. The efficacy of CPP has been demonstrated with maltreated and other high-risk populations. This evaluation will examine optimal timing of CPP (beginning prenatally or postnatally) and optimal duration of services (6 vs. 12 months). Additionally, how and for whom CPP is most effective and why will be examined. Assessments of parenting, maternal sensitivity, representational models, cognitions, physiological reactivity, and physical health indicators will be assessed prenatally, and at children's age of 3, 9, and 12 months.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedJan 18, 2019
Enrollment StartFeb 21, 2019
Primary CompletionDec 30, 2024
Study CompletionDec 31, 2024
TodayJul 2, 2026
Enrollment to primary: 5.9 yearsPosted 7.5 years ago

Interventions

Child-Parent Psychotherapy (CPP)behavioral

Child-Parent Psychotherapy (CPP) focuses on parent-infant relationships, increases efficacy for improved mother-child relationships, more sensitive parenting, healthier child development, and maltreatment prevention. A primary goal is to strengthen the parent-child relationship to improve family functioning and child security of attachment. Through respect, empathic concern, and positive regard, the therapeutic relationship provides mothers with corrective emotional experiences, through which they are able to differentiate current from past relationships, form positive internal representations of themselves and of themselves in relationship to others, particularly their children. Parents are encouraged to process their experiences of trauma and restore parental roles as protective shields, improve affective regulation capacities, enhance understanding of the meaning of behavior, acknowledge the impact of trauma, and support children in a more positive developmental trajectory.

Community Health Worker (CHW) home visitationbehavioral

Community Health Worker (CHW) home visitation includes assistance with concrete support needs, such as transportation to medical appointments, referrals for food, housing, and employment services, and attention to developmental needs of young children.