CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 40 enrolled
Drug / intervention
Dexmedetomidine +3 moredrug
Likely dose
Morphine Sulfate 3mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03809182
NCT03809182Phase 4Completed
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Effect of Dexmedetomidine on Postoperative Glucose Levels and Insulin Secretion Patterns in Obese Patients With Impaired Glucose Tolerance.

Pontificia Universidad Catolica de Chile·interventional·Posted Jan 18, 2019·Updated Oct 1, 2020

In Brief

A Phase 4 clinical trial evaluating Dexmedetomidine, 0.9% Sodium-chloride, and 2 other interventions for Bariatric Surgery Candidate and 2 related conditions. Completed, enrolled 40 participants.

Detailed Summary

This study investigated the effect of dexmedetomidine in obese patients undergoing bariatric surgery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBariatric Surgery Candidate, Glucose Intolerance, Insulin Resistance
Countries--
Collaborators--

Timeline

Phase 4CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedJan 18, 2019
Enrollment StartSep 27, 2012
Primary CompletionJul 25, 2013
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 7.5 years ago

Interventions

Dexmedetomidinedrug

A bolus of 1ug/kg in 10 minutes, followed by an infusion of 0.5ug/kg/h until the end of surgery.

0.9% Sodium-chloridedrug

The same infusion rate used in the dexmedetomidine group.

Fentanyldrug

Intraoperative fentanyl was given in case of 25% increment in the blood pressure and/or heart rate in comparison to baseline (previous anesthesia induction).

Morphine Sulfatedrug

Boluses of 3mg of intravenous morphine were given in the postoperative acute care unit. Once the pain score was equal or less than 3/10 the patient-controlled analgesia pumps were installed and the patients were discharged to their room.