CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 359 enrolled
Drug / intervention
Intensive Cognitive Behavior Therapy (iCBT) +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03810456
NCT03810456Phase 3Completed
CompareCT.gov

Improving Veteran Functioning With Intensive Transdiagnostic CBT for Anxiety

VA Office of Research and Development·interventional·Posted Jan 18, 2019·Updated Aug 28, 2023

In Brief

A Phase 3 clinical trial evaluating Intensive Cognitive Behavior Therapy (iCBT) and Standard Cognitive Behavior Therapy (sCBT) for Anxiety Disorders. Completed, enrolled 359 participants across 1 site.

Detailed Summary

This study is a randomized controlled trial examining the effectiveness of a transdiagnostic cognitive behavioral treatment (CBT) in improving Veterans' community reintegration and quality of life. Veterans with anxiety-based disorders, including posttraumatic stress, panic, social anxiety, and generalized anxiety disorders (with or without co-occurring depression) will be randomized to an intensive CBT (iCBT) treatment delivered over one weekend, standard CBT (sCBT) delivered over 12 weeks or treatment as usual (TAU). The study will also evaluate the potential of the compressed weekend format of iCBT in producing more rapid improvement in outcomes and increasing psychotherapy engagement compared with a standard psychotherapy format. Qualitative interviews will be conducted with Veterans who receive iCBT and their family members to examine how iCBT and environmental factors impacted their process of recovery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAnxiety Disorders
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
20192020202120222023202420252026
First PostedJan 18, 2019
Enrollment StartAug 1, 2018
Primary CompletionAug 31, 2021
Study CompletionAug 31, 2022
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 7.5 years ago

Interventions

Intensive Cognitive Behavior Therapy (iCBT)behavioral

Participants randomized to iCBT will receive 16 hours of cognitive behavioral therapy for anxiety over one weekend. The treatment entails psychoeducation, cognitive restructuring and exposure exercises.

Standard Cognitive Behavior Therapy (sCBT)behavioral

Participants randomized to sCBT will receive 16 hours of cognitive behavioral therapy for anxiety weekly over a period of 12 weeks. The treatment entails psychoeducation, cognitive restructuring and exposure exercises.