CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 240 enrolled
Drug / intervention
Vixarelimab +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03816891
NCT03816891Phase 2Completed

A Phase 2a/b, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of KPL-716 in Reducing Pruritus in Subjects With Prurigo Nodularis

Genentech, Inc.·interventional·Posted Jan 25, 2019·Updated Jan 13, 2026

In Brief

A Phase 2 clinical trial evaluating Vixarelimab and Placebo for Prurigo Nodularis and Pruritis. Completed, enrolled 240 participants across 86 sites in 13 countries.

Detailed Summary

Study of the efficacy, safety, tolerability, pharmacokinetics (PK), and immunogenicity of Vixarelimab (KPL-716) in subjects with prurigo nodularis (PN).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Austria, Belgium, Canada, Czechia, France, Germany, Italy, Poland, South Korea, Taiwan, United Kingdom, United States

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedJan 25, 2019
Enrollment StartMar 11, 2019
Primary CompletionDec 28, 2022
Study CompletionAug 24, 2023
TodayJul 2, 2026
Enrollment to primary: 3.8 yearsPosted 7.4 years ago

Interventions

Vixarelimabdrug

solution for injection

Placebodrug

solution for injection