CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 268 enrolled
Drug / intervention
Education microlearning sessions +3 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03817229
NCT03817229N/ACompleted

Fostering Medication Adherence in Children With Epilepsy Using mHealth Technology

Children's Hospital Medical Center, Cincinnati·interventional·Posted Jan 25, 2019·Updated Oct 30, 2025

In Brief

A clinical study evaluating Education microlearning sessions, Automated digital reminders, and 2 other interventions for Epilepsy. Completed, enrolled 268 participants across 4 sites.

Detailed Summary

Fifty-eight percent of children with new-onset epilepsy do not take their antiepileptic drugs (AEDs) as prescribed, which is associated with continued seizures, mortality, poor quality of life, and high healthcare costs. Evidence-based adherence interventions are lacking and critically needed, especially for children with epilepsy, who represent an underserved population in pediatrics. The current proposal is a mHealth sequential, multiple assignment, randomized trial (SMART) focused on providing education, automated digital reminders, and individualized adherence feedback, as well as teaching problem-solving skills, with the goal of improving adherence and quality of life and decreasing seizures and health care utilization.

Study Details

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedJan 25, 2019
Enrollment StartApr 15, 2019
Primary CompletionJun 15, 2024
Study CompletionAug 1, 2024
TodayJul 2, 2026
Enrollment to primary: 5.2 yearsPosted 7.4 years ago

Interventions

Education microlearning sessionsbehavioral

mHealth education microlearning sessions

Automated digital remindersbehavioral

reminders from electronic monitors based on texts or lights/chimes

Problem-solving mHealth modulebehavioral

mhealht problem solving module with 2 telehealth sessions with a therapist

Individualized Adherence Feedback Reportbehavioral

Individual Adherence Feedback reports sent to parents weekly