CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 20 enrolled
Drug / intervention
Vitamin C +1 moredrug
Likely dose
Vitamin C 200mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03829683
NCT03829683Phase 2Completed
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Vitamin C Infusion for TReatment in Sepsis and Alcoholic Hepatitis

Virginia Commonwealth University·interventional·Posted Feb 4, 2019·Updated Aug 28, 2023

In Brief

A Phase 2 clinical trial evaluating Vitamin C and Dextrose 5% in water for Alcoholic Hepatitis and Sepsis. Completed, enrolled 20 participants across 1 site.

Detailed Summary

The purpose of this research study is to test the safety, tolerability, and effectiveness of Vitamin C (ascorbic acid) intravenous infusion when used to treat alcoholic hepatitis (inflammation of the liver from heavy alcohol use) and sepsis (life-threatening complication of an infection).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAlcoholic Hepatitis, Sepsis
CountriesUnited States
CollaboratorsNational Institute on Alcohol Abuse and Alcoholism (NIAAA)

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedFeb 4, 2019
Enrollment StartApr 16, 2019
Primary CompletionMar 31, 2022
Study CompletionJun 23, 2022
TodayJul 2, 2026
Enrollment to primary: 3.0 yearsPosted 7.4 years ago

Interventions

Vitamin Cdrug

200mg/kg/24hours

Dextrose 5% in waterdrug

50mL intravenously every 6 hours