At a glance
ClinicalIndex Comparison RecordPhase 3Completed· 154 enrolled
Drug / intervention
Low-Dose Bupivacaine +1 moredrug
Likely dose
Low-Dose Bupivacaine 10 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Double Blind Randomized Clinical Trial Comparing Time To Return of Lower Extremity Motor Function Following Spinal Anesthetic With Mepivacaine Versus Low-Dose Bupivacaine For Primary Total Hip and Knee Arthroplasty
In Brief
A Phase 3 clinical trial evaluating Low-Dose Bupivacaine and Mepivacaine for Knee Osteoarthritis and Hip Osteoarthritis. Completed, enrolled 154 participants across 1 site.
Detailed Summary
This research is being done to see if there is a difference between two different spinal anesthetics (Mepivacaine vs. Bupivacaine) as it relates to reducing post-operative complications and the time it takes for subjects to regain mobility after surgery.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsKnee Osteoarthritis, Hip Osteoarthritis
CountriesUnited States
Collaborators--
Timeline
Phase 3CompletedFinished
20192020202120222023202420252026
First PostedFeb 2019
Enrollment StartFeb 2019
Primary CompletionOct 2019
TodayJul 2026
First PostedFeb 12, 2019
Enrollment StartFeb 25, 2019
Primary CompletionOct 29, 2019
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 7.4 years ago
Interventions
Low-Dose Bupivacainedrug
10 mg (2 mL of 0.5%) administered as an isobaric spinal anesthetic
Mepivacainedrug
70 mg (3.5 mL of 2%) administered as an isobaric spinal anesthetic