CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 64 enrolled
Drug / intervention
TG4050drug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03839524
NCT03839524Phase 1Completed

A Phase I Trial Evaluating a Mutanome-directed Immunotherapy in Patients With High Grade Serous Carcinoma (HGSC) of the Ovary, Fallopian Tube or Peritoneum.

Transgene·interventional·Posted Feb 15, 2019·Updated Nov 14, 2025

In Brief

A Phase 1 clinical trial evaluating TG4050 for Ovarian Carcinoma and 2 related conditions. Completed, enrolled 64 participants across 6 sites in 2 countries.

Detailed Summary

This is a multicenter, open-label, single arm phase I study evaluating the safety and tolerability as well as some activity parameters of TG4050 in patients with ovarian, fallopian or peritoneal serous carcinoma.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesFrance, United States
Collaborators--

Timeline

Phase 1CompletedFinished
20192020202120222023202420252026
First PostedFeb 15, 2019
Enrollment StartDec 9, 2019
Primary CompletionOct 8, 2024
TodayJul 2, 2026
Enrollment to primary: 4.8 yearsPosted 7.4 years ago

Interventions

TG4050drug

Subcutaneous injections weekly for the first 6 weeks and then every 3 weeks.