CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 94 enrolled
Drug / intervention
Safinamide Methanesulfonate +1 moredrug
Likely dose
Safinamide Methanesulfonate 50 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03841604
NCT03841604Phase 4Completed

A Randomised, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Safinamide 100mg Once Daily, as add-on Therapy, in Idiopathic Parkinson's Disease (PD) Patients With Motor Fluctuations and PD Related Chronic Pain

Zambon SpA·interventional·Posted Feb 15, 2019·Updated May 22, 2023

In Brief

A Phase 4 clinical trial evaluating Safinamide Methanesulfonate and Safinamide methanesulfonate matching placebo for Idiopathic Parkinson Disease. Completed, enrolled 94 participants across 45 sites in 5 countries.

Detailed Summary

Primary objective: • To evaluate the potential efficacy of safinamide 100 mg once daily (OD), compared with placebo, as add-on therapy for PD-related chronic pain Secondary objectives: * Percentage of pain responders * Clinical Global Impression for pain * Patient Global Impression for pain * Reduction in use of pain drugs * Mood * Motor and non-motor symptoms Safety Objectives: • Safety and tolerability

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustria, France, Germany, Italy, Spain
Collaborators--

Timeline

Phase 4CompletedFinished
20192020202120222023202420252026
First PostedFeb 15, 2019
Enrollment StartApr 9, 2019
Primary CompletionApr 30, 2021
Study CompletionMay 3, 2021
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 7.4 years ago

Interventions

Safinamide Methanesulfonatedrug

50 mg, 100 mg

Safinamide methanesulfonate matching placeboother

50 mg, 100 mg