CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 7 enrolled
Drug / intervention
Activated Inspire® Upper Airway Stimulation System +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03844295
NCT03844295N/ACompleted

Upper AIRway Implanted Nerve STIMulation Therapy: A Breakthrough in Obstructive Sleep Apnea Therapy

University Hospital, Grenoble·interventional·Posted Feb 18, 2019·Updated Jul 26, 2024

In Brief

A clinical study evaluating Activated Inspire® Upper Airway Stimulation System and Inactivated Inspire® Upper Airway Stimulation System for Obstructive Sleep Apnea Syndrome. Completed, enrolled 7 participants across 1 site.

Detailed Summary

Continuous positive airway pressure (CPAP) is the gold standard to normalize breathing during sleep in patients with obstructive sleep apnea syndrom (OSA). Many patients will not tolerate or will not accept CPAP. Implanted nerve stimulation is a novel therapy for OSA patients that restores the upper airway potency using unilateral XII nerve electric stimulation. The principal objective of this study is short-term efficacy of a new treatment for OSA on blood pressure variability during sleep.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesFrance

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedFeb 18, 2019
Enrollment StartMar 21, 2019
Primary CompletionDec 22, 2021
Study CompletionOct 10, 2023
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 7.4 years ago

Interventions

Activated Inspire® Upper Airway Stimulation Systemdevice

At first, INSPIRE® device will be active a month

Inactivated Inspire® Upper Airway Stimulation Systemdevice

After 15 days "wash-out" INSPIRE® device will be inactivated for a second period of one month.