At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Preoperative Gabapentin Versus Bisoprolol for Intraoperative Hemodynamic and Surgical Field Optimization During Endoscopic Sinus Surgery
In Brief
A Phase 4 clinical trial evaluating Gabapentin1200 mg, bisoprolol 2.5mg, and 1 other intervention for Blood Pressure. Completed, enrolled 63 participants.
Detailed Summary
the current study hypothesized that Gabapentin can be effective as Bisoprolol in reduction of intraoperative bleeding, improving the operative's field visibility and increase the surgeon satisfaction via optimization of blood pressure and heart rate . A prospective randomized double blinded controlled study. Eligible patients were randomized according to random list generated software and allocated into 3 equal and matched groups (15 patients in each group):- * Group G: gabapentin group in which Patients were premedicated with oral gabapentin 1200 mg (Conventin 400mg; Evapharm) with sips of water, 2 hours before induction of anesthesia. * Group B: bisoprolol group in which Patients were premedicated with oral bisoprolol 2.5 mg ( Concor 2.5mg ; Merck/Amoun ) with sips of water, 2 hours before induction of anesthesia. * Group C: control group in which Patients were premedicated with oral placebo with sips of water, 2 hours before induction of anesthesia.
Study Details
Timeline
Interventions
patients received 1200mg gabapentin 2 hrs preoperative
patients received 2.5mg bisoprolol 2 hrs preoperative
patients received oral placebo 2 hrs preoperative