CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 200 enrolled
Drug / intervention
BI 425809 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03859973
NCT03859973Phase 2Completed

A Phase II Randomized, Double-blinded, Placebo-controlled Parallel Group Trial to Examine the Efficacy and Safety of BI 425809 Once Daily With Adjunctive Computerized Cognitive Training Over 12 Week Treatment Period in Patients With Schizophrenia

Boehringer Ingelheim·interventional·Posted Mar 1, 2019·Updated Nov 18, 2023

In Brief

A Phase 2 clinical trial evaluating BI 425809 and Placebo for Schizophrenia. Completed, enrolled 200 participants across 50 sites in 6 countries.

Detailed Summary

This is a study in adults with schizophrenia. The study tests whether a medicine called BI 425809 together with brain training improves mental abilities. Participants take study medication once a day for 12 weeks. At the start of the study, the participants are put into 2 groups. It is decided by chance who gets into which group. One group gets BI 425809 tablets every day. The other group gets placebo tablets every day. Placebo tablets look like the BI 425809 tablets, but contain no medicine. During the study, all participants do brain training using a computer. The doctors regularly test mental abilities of the participants. The results of the mental ability tests are compared between the groups. The doctors also check the general health of the patients.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSchizophrenia
CountriesAustralia, Canada, France, New Zealand, United Kingdom, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedMar 1, 2019
Enrollment StartApr 15, 2019
Primary CompletionSep 30, 2022
Study CompletionNov 4, 2022
TodayJul 2, 2026
Enrollment to primary: 3.5 yearsPosted 7.3 years ago

Interventions

BI 425809drug

Tablet

Placebodrug

Tablet