CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 89 enrolled
Drug / intervention
Subcuticular Sutures - Surgeon 1 +3 moreprocedure
Likely dose
Dermabond PRINEO applied over running sutures for deep and subcuticular layer closureAI-extracted
Key inclusion· 4
  • Age 18 years or older
  • Undergoing primary total shoulder arthroplasty performed by the principal or co-investigator
  • Willing and able to provide informed consent
  • Able to continue post-operative follow-up care at MUSC with operating surgeons
Key exclusion· 6
  • Tattoo or skin marking within 2 inches of intended surgical incision site
  • Known hypersensitivity to cyanoacrylate, formaldehyde, benzalkonium chloride, or pressure sensitive adhesive
  • Prior ipsilateral shoulder arthroplasty or other open ipsilateral shoulder surgery via deltopectoral approach
  • HIV-positive or otherwise immunocompromised status

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03860181
NCT03860181N/ACompleted

Investigation of a New Skin Closure Device, Dermabond PRINEO, for Total Shoulder Arthroplasty: A Randomized, Controlled Trial

Medical University of South Carolina·interventional·Posted Mar 1, 2019·Updated Oct 1, 2021

In Brief

A clinical study evaluating Subcuticular Sutures - Surgeon 1, Metal Staples - Surgeon 2, and 2 other interventions for Surgical Wound and 2 related conditions. Completed, enrolled 89 participants across 1 site.

Detailed Summary

This is a research study to find out whether wound closure (the process of closing the surgical wound after the procedure is complete) with Dermabond PRINEO Skin Closure System (PRINEO) will be faster and improve wound healing compared to standard closing methods after total shoulder replacement. The PRINEO system involves using running stitches to close the wound, and then taping over the sutures with a sticky film that holds the wound closed.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsJohnson & Johnson

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedMar 1, 2019
Enrollment StartMar 25, 2019
Primary CompletionJun 23, 2020
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 7.3 years ago

Interventions

Subcuticular Sutures - Surgeon 1procedure

This intervention closes incisions after shoulder arthroplasty using subcuticular sutures with Dermabond.The deep layer closure will require interrupted sutures.

Metal Staples - Surgeon 2procedure

This intervention closes incisions after shoulder arthroplasty with metal staples. The deep layer closure will require interrupted sutures,

PRINEO - Surgeon 1device

The closure system uses the Dermabond PRINEO (which is similar to clear tape stuck over the wound) placed over running sutures for both the deep and subcuticular layer.

PRINEO - Surgeon 2device

The closure system uses the Dermabond PRINEO (which is similar to clear tape stuck over the wound) placed over running sutures for both the deep and subcuticular layer.