CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 443 enrolled
Drug / intervention
Tirzepatide +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03861039
NCT03861039Phase 3Completed

A Phase 3, Long-Term Safety Study of Tirzepatide in Combination With Monotherapy of Oral Antihyperglycemic Medications in Patients With Type 2 Diabetes Mellitus (SURPASS J-combo)

Eli Lilly and Company·interventional·Posted Mar 4, 2019·Updated Feb 14, 2022

In Brief

A Phase 3 clinical trial evaluating Tirzepatide and Oral antihyperglycemic medication (OAM) for Type 2 Diabetes Mellitus. Completed, enrolled 443 participants across 34 sites.

Detailed Summary

The purpose of this study is to determine the long-term safety of the study drug tirzepatide in combination with oral antihyperglycemic medications in participants with type 2 diabetes.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesJapan
Collaborators--

Timeline

Phase 3CompletedFinished
20192020202120222023202420252026
First PostedMar 4, 2019
Enrollment StartMar 30, 2019
Primary CompletionJan 26, 2021
Study CompletionFeb 16, 2021
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 7.3 years ago

Interventions

Tirzepatidedrug

Administered SC

Oral antihyperglycemic medication (OAM)drug

Oral antihyperglycemic medication (OAM): Sulfonylurea, biguanide, alpha-glucosidase inhibitor, thiazolidinedione, glinide, or sodium-glucose cotransporter type 2 inhibitor.