At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Comparison of NSAIDs for Acute, Non-radicular Low Back Pain. A Randomized Trial
In Brief
A Phase 4 clinical trial evaluating Ketorolac, Ibuprofen, and 2 other interventions for Back Pain Without Radiation and Low Back Pain. Completed, enrolled 198 participants across 1 site.
Detailed Summary
Purpose: This is a randomized clinical trial comparing the effects of three different medications for acute low back pain (LBP):Ketorolac, Ibuprofen, Diclofenac Hypothesis: A daily regimen of ketorolac will provide greater relief of LBP than ibuprofen or diclofenac 5 days after an emergency department (ED) visit, as measured by the Roland Morris Disability Questionnaire (RMQ)
Study Details
Timeline
Interventions
Participants may be randomized to receive Ketorolac oral medication 10 mg, every 8 hours for 5 days as needed
Participants may be randomized to receive Ibuprofen oral medication 600 mg, every 8 hours for 5 days as needed
Participants may be randomized to receive Diflofenac oral medication 50 mg, every 8 hours for 5 days as needed
Research personnel will provide each patient with a 15-minute educational intervention. This will be based on National Institute of Arthritis and Musculoskeletal and Skin Diseases Handout on Health: Back Pain information